Hezbollah launched a ballistic missile at Tel Aviv early on Wednesday, in a further escalation after Israel carried out strikes on Lebanon that killed hundreds of people.

The Israeli military said it intercepted the surface-to-surface missile, which set off air raid sirens in Tel Aviv and across central Israel, and there were no reports of casualties or damage.

The military said it struck the site in southern Lebanon from which the projectile was launched.

Hezbollah said it fired a Qader 1 ballistic missile targeting the headquarters of Israel’s Mossad intelligence agency, which it blames for a recent string of targeted killings of its top commanders and for an attack last week in which bombs hidden in pagers and walkie-talkies killed dozens of people and wounded thousands, including many Hezbollah members.

The Israeli military said it was the first time a projectile fired from Lebanon had reached central Israel.

Hezbollah claimed to have targeted an intelligence base near Tel Aviv last month in an aerial attack, but there was no confirmation. The Palestinian Hamas militant group in Gaza repeatedly targeted Tel Aviv in the opening months of the war.

Smoke rises from Israeli airstrikes in southern Lebanon
Smoke rises from Israeli airstrikes in the southern village of Kfar Rouman, seen from Marjayoun, south Lebanon, on Wednesday (Hussein Malla/AP)

Lt Col Nadav Shoshani, an Israeli military spokesperson, said the missile fired on Wednesday had a “heavy warhead” but declined to elaborate or confirm it was the type described by Hezbollah.

He dismissed Hezbollah’s claim of targeting the Mossad headquarters, located just north of Tel Aviv, as “psychological warfare”.

The Iranian-made Qader is a medium-range surface-to-surface ballistic missile with multiple types and payloads.

It can carry an explosive payload of up to 800kg (1,760 pounds), according to the Washington-based Centre for Strategic and International Studies. Iranian officials have described the liquid-fuelled missile as having a range of 2,000km (1,240 miles).

The launch ratcheted up tensions as the region appears to be teetering toward another all-out war, even as Israel continues to battle Hamas in the Gaza Strip.

Later, first responders said two people were wounded by a rocket fired into northern Israel from Lebanon.

The Magen David Adom rescue service said a 32-year-old man was seriously wounded and a 52-year-old was moderately wounded by shrapnel in the agricultural village of Kibbutz Saar.

A wave of Israeli strikes on Monday and Tuesday killed at least 560 people in Lebanon and forced thousands to seek refuge.

Smoke rises from an Israeli airstrike on a village
Smoke rises from an Israeli airstrike on the village of Khiam (Hussein Malla/AP)

Families have fled southern Lebanon, flocking to Beirut and the coastal city of Sidon, sleeping in schools turned into shelters, as well as in cars, parks and along the beach. Some sought to leave the country, causing a traffic jam at the border with Syria.

Israel said late on Tuesday that fighter jets carried out “extensive strikes” on Hezbollah weapons and rocket launchers across southern Lebanon and in the Bekaa region to the north.

On Wednesday it responded with its own new strikes on Hezbollah. In Lebanon, at least three people were killed and nine wounded in a strike near Byblos, according to the country’s health ministry. The coastal town is north of Beirut and far from Hezbollah’s main strongholds.

The military has said it has no immediate plans for a ground invasion but has declined to give a timetable for the air campaign.

The UN Security Council scheduled an emergency meeting on Lebanon for Wednesday at the request of France.

Relatives carry the body of a young girl
Relatives carry the body of a young girl, killed in an Israeli airstrike, during her funeral procession in the southern village of Saksakieh, Lebanon (Mohammed Zaatari/AP)

Nearly a year of fighting between Hezbollah and Israel had already displaced tens of thousands of people on both sides of the border before this week’s escalation.

Israel has vowed to do whatever it takes to ensure its citizens can return to their homes in the north, while Hezbollah has said it will keep up its rocket attacks until there is a ceasefire in Gaza.

Israel has moved thousands of troops who had been serving in Gaza to the northern border. It says Hezbollah has some 150,000 rockets and missiles, including some capable of striking anywhere in Israel, and that the group has fired some 9,000 rockets and drones since last October.

Cross-border exchanges began ramping up on Sunday in the wake of the pager and walkie-talkie bombings, which killed 39 people and wounded nearly 3,000, many of them civilians.

Lebanon blamed Israel, but Israel did not confirm or deny responsibility.

A police officer next to a bomb crater in Lebanon
A Lebanese police intelligence officer stands near a crater at the site of an Israeli airstrike that hit a hangar in the southern town of Jiyeh, Lebanon, on Wednesday (Mohammed Zaatari/AP)

On Sunday, Hezbollah launched around 150 rockets, missiles and drones into northern Israel.

The next day, Israel said its warplanes struck 1,600 Hezbollah targets, destroying cruise missiles, long and short-range rockets and attack drones, including weapons concealed in private homes.

The strikes racked up the highest one-day death toll in Lebanon since Israel and Hezbollah fought a bruising monthlong war in 2006.

An Israeli airstrike in Beirut on Tuesday killed Ibrahim Kobeisi, who Israel described as a top Hezbollah commander with the group’s rocket and missile unit.

It was the latest in a string of assassinations and other setbacks for Hezbollah, which is Lebanon’s strongest political and military actor and is widely considered the top paramilitary force in the Arab world.

Lebanon’s Health Ministry said six people were killed and 15 were wounded in the strike in a southern Beirut suburb, an area where Hezbollah has a strong presence.

The UN’s High Commissioner for Refugees in Lebanon said one of its staffers and her young son were among those killed on Monday in the Bekaa region, while a cleaner under contract was killed in a strike in the south.

Hezbollah fired 300 rockets on Tuesday, injuring six Israeli soldiers and civilians, most of them lightly, according to the Israeli military.

The Lebanese Health Ministry said at least 564 people have been killed in Israeli strikes since Monday, including 50 children and 94 women, and that more than 1,800 have been wounded.

Israeli Prime Minister Benjamin Netanyahu will travel to the United Nations this week with no end in sight to the war in Gaza, the conflict with Hezbollah intensifying and his and Israel’s international legitimacy at a low.

Mr Netanyahu will head to New York burdened also by what could be an imminent warrant for his arrest by the International Criminal Court.

Meanwhile, 700 British troops were due to arrive on Wednesday on the Mediterranean island of Cyprus as the UK prepared for the possible evacuation of its citizens from Lebanon.

An Israeli firefighter plane flies over woodland in northern Israel
An Israeli firefighter plane above an open area near the city of Safed, northern Israel (Leo Correa/AP)

Egypt, Jordan and Iraq say Israel is pushing the Middle East into an all-out war and are calling on the United Nations Security Council to intervene.

In a joint statement on Wednesday, the three countries’ foreign ministers affirmed that averting a regional war requires the cessation of “the Israeli aggression on Gaza”.

The ministers also condemned the Israeli aggression on Lebanon, and said that “Israel is pushing the region into an all-out war”.

On Wednesday Pope Francis called for a stop to escalating tensions in Lebanon, calling the situation “unacceptable”.

“I am saddened by the news coming from Lebanon, where intense bombing in recent days has caused much death and destruction,” the pope said during a regular audience at the Vatican.

“I hope that the international community will make every effort to stop this terrible escalation. It is unacceptable. I express my closeness to the Lebanese people, who have already suffered too much in the recent past.”